Over long, hard decades, American winemakers have won the respect of connoisseurs everywhere. Many of the world's most cherished, and expensive, wines come fro the United States.. But today, the unique and eccentric wine industry faces agrim set of challenges that could transform it forever: oversupply in the face of flat consumption, devastating vineyard diseases, an antiquated distribution system, fierce competition from abroad, attacks from anti-alcohol forces, and an inability to capitalize on wine's proven health benefits.